• Prospecting biotechnologically-relevant monooxygenases from cold sediment metagenomes: An in silico approach 

      Musumeci, Matias A.; Lozada, Mariana; Rial, Daniela V.; Cormack, Walter P. Mac; Jansson, Janet K.; Sjöling, Sara; Carroll, JoLynn; Dionisi, Hebe M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-09)
      The goal of this work was to identify sequences encoding monooxygenase biocatalysts with novel features by in silico mining an assembled metagenomic dataset of polar and subpolar marine sediments. The targeted enzyme sequences were Baeyer–Villiger and bacterial cytochrome P450 monooxygenases (CYP153). These enzymes have wide-ranging applications, from the synthesis of steroids, antibiotics, mycotoxins ...
    • Selection, Succession and Stabilization of Soil Microbial Consortia 

      Zegeye, Elias; Brislawn, Colin; Farris, Yulia; Fansler, Sarah; Hofmockel, Kirsten; Jansson, Janet K.; Wright, Aaron; Graham, Emily; Naylor, Dan; McClure, Ryan S.; Bernstein, Hans Christopher (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-14)
      Soil microorganisms play fundamental roles in cycling of soil carbon, nitrogen, and other nutrients, yet we have a poor understanding of how soil microbiomes are shaped by their nutritional and physical environment. In this study, we investigated the successional dynamics of a soil microbiome during 21 weeks of enrichment on chitin and its monomer, N-acetylglucosamine. We examined succession of the ...